The state of dairy sheep farming and prospects for the use of genomic methods to improve sheep productivity and milk composition
https://doi.org/10.26897/2074-0840-2024-1-3-9
Abstract
The world production of sheep milk has more than doubled in the last 50 years. However, sheep milk and sheep milk products have not yet become a traditional consumer product in Russia. One of the main reasons for this is the lack of specialised dairy breeds of sheep and insufficient use of modern breeding methods, including marker‑assisted selection. The article considers the main candidate genes of sheep dairy productivity, shows their influence on milk yield, fat and protein content, resistance to mastitis.
About the Authors
M. I. SelionovaRussian Federation
Selionova Marina Ivanovna - Doctor of Biological Sciences, Professor, Head of the Department of Breeding, Genetics and Biotechnology of Animals of the Russian State Agricultural Academy named after K.A. Timiryazev.
127550, Moscow, Timiryazevskaya str., 52; tel.: (968) 266-33-03
A-M. M. Aybazov
Russian Federation
Aybazov Ali-Mahomet Mussayevich - Doctor of Agricultural Sciences, Professor, Chief Scientific Officer. employee, All-Russian Research Institute of Sheep and Goat Breeding – branch of the North Caucasus Federal Agrarian Scientific Center.
Stavropol, per. Zootechnical, 15; tel.: (938) 351-01-02
M. Yu. Gladkikh
Russian Federation
Gladkikh Marianna Yurievna - Candidate of Agricultural Sciences, Associate Professor, Scientist. employee of the Department of Animal Breeding, Genetics and Biotechnology of the RSAA named after K.A. Timiryazev.
52 Timiryazevskaya str., Moscow, 127550; tel.: (919) 970-72-97
References
1. Al-Mamun H.A., Kwan P., Clark S.A., Ferdosi M.H., Tellam R., Gondro C. Genome-wide association study of body eight in Australian Merino sheep reveals an ortholo-gous region on OAR6 to human and bovine genomic regions affecting height and weight • Genetics Selection Evolution. 2015. 47(1). P. 1-11.
2. Bozgo V, Hoda A., Hysi L., Papa L. Genetic polymorphism detection of Casein genes in Albanian local sheep breeds • Livestock Research for Rural Development. 2020. 32(5). Article 71.
3. Bozhilova-Sakova M., Dimitrova I., Ivanova T., Koutev V., Ignatova M. Polymorphism of ABCG2 gene and its effects on litter size and milk production of synthetic population Bulgarian milk ewes • Tradition and Modernity in Veterinary Medicine. 2022. 7(1). P. 44-48.
4. Calvo J.H., Marcos S., Jurado J.J., Serrano M. Association of the heart fatty acid-binding protein (FABP3) gene with milk traits in Manchega breed sheep • Animal Genetics. 2004. 35(4). P. 347-349.
5. Dimitrova I., Bozhilova-Sakova M., Ignatova M., Koutev V., Genova K. Investigation of ABCG2 gene in three fine fleece sheep breeds in Bulgaria • Tradition and modernity in veterinary medicine. 2022. V. 7. 1(12). P. 44-48.
6. Elyasi G., Shodja J., Nassiri M., Tahmasebi A., Pira-hary O., Javanmard A. Polymorphism of p-lactoglobulin gene in Iranian sheep breeds using PCRR FLP • Journal of molecular Genetics. 2010. 2 (1). P. 6-9.
7. Gencheva D., Georgieva S. Genetic diversity and population structure of Bulgarian autochthonous sheep breeds based on nucleotide variation in Alpha S1-casein gene • Bulgarian Journal of Agricultural Science. 2019. 25(3). P. 95-102.
8. Georgios B., Clark S., Bush P.G., Bramis G., Ar-senos D.A., Psifidi A. Genetic and genomic analyses underpin the feasibility of concomitant genetic improvement of milk yield and mastitis resistance in dairy sheep • PLoS One. 2019.14: e0214346.
9. Gras M., Pistol G., Pelmus R., Lazar C., Grosu H., Ghita E. Relationship between gene polymorphism and milk production traits in Teleorman Black Head sheep breed • Revista MVZ Cordoba. 2016. 21(1). P. 5124-5136.
10. Gutierrez-Gil B., Arranz J.J., Wiener P. An interpretive review of selective sweep studies in Bos Taurus cattle populations: Identification of unique and shared selection signals across breeds • Front. Genet. 2015. 6. P. 167.
11. Kalaydjiev G., Angelova T., Yordanova D., Karabashev V., Laleva S., Cassandro M., Krastanov J., Oblakov N., Dimov D., PopovaY. „D-allele” frequencies in milk a-s1 casein from Bulgarian local sheep breeds • LXVIII Convegno Sisvet, XI Convegno Aipvet e XII Con-vegno Sira,16-18 June 2014, Pisa, Italy P. 142-145.
12. Kalaydzhiev G.I., Balabanova T.B., Ivanova M.G., Ivanov G.Y. Correlation between phenotypic characteristics of chemical composition and rennet coagulation of sheep milk • In IOP Conference Series: Materials Science and Engineering. 2021. 1031(1). P. 012099).
13. Kowalewska-Luczak I., Czerniawska-Pi^tkowska E., Pecka-Kielb E. Investigation on relationships of the FABP3 and SLC27A3 genes with milk production traits in sheep • J. Elemental. 2017. 22. P. 1485-1493.
14. Mateescu R.G., Thonney M.L. Genetic mapping of quantitative trait loci for milk production in sheep • Animal genetics. 2010. 41(5). P. 460-466.
15. Oner Y., Orman A., Ustuner H., Yilmaz A. Investigation of polymorphisms on ABCG2, AANAT and FABP3 genes in the Kivircik sheep reared in three different provinces of Turkey • Kafkas Univ. Vet. Fak. Derg. 20. P. 649-654.
16. Othman O.E., El-Fiky S.A., Hassan N.A., Mahfouz E.R., Balabel E.A. Genetic polymorphism detection of two a-Casein genes in three Egyptian sheep breeds • Journal of Genetic Engineering and Biotechnology. 2013. 11(2). P. 129-134.
17. Panayotov D., Sevov S., Georgiev D. Milk yield and morphological characteristics of the udder of sheep from the breed Lacaune in Bulgaria • Bulgarian Journal of Agricultural Science. 2018. 24(1). P. 95-100.
18. Popescu А, Stanciu М, Antonie L. Livestock and milk and meat production in the top five EU countries rearing sheep and goats, 2012-2021 • Scientific Papers Series Management, Economic Engineering in Agriculture and Rural Development. 2022. Vol. 22, Issue 3, 2022. Р. 2284-7995.
19. Stancheva N. Productivity and heredity of some traits of sheep from the Synthetic Bulgarian Dairy Population • Livestock sciences. 2013. 6. P. 29-35.
20. Suarez-Vega A., Gutierrez-Gil B., Klopp C., Toss-er-Klopp G., Arranz J.J. Variant discovery in the sheep milk transcriptome using RNA sequencing • BMC Genomics. 2017. 18. P. 170.
21. Sumantri C., Herdiana D., Farajallah A., Rahmat D. Polymorphism of Pituitary-Specific Transcription Factor-1 (Pit-1) Gene at Locus (Pit-1-Hinf1) and its effects on dam body weight and milk production of local sheep’s • Jurnal Ilmu Ternak dan Veteriner. 2009. 14(3). P. 212-229.
22. Thomas D.L., Berger Y.M., McKusick B.C., Gottfredson R.G. Comparison of East Friesian-crossbred and Lacaune-crossbred ewe lambs for dairy sheep production first-year results from a multiyear trial • In Dairy Sheep Symposium. 2020. http://babcock.wisc.edu/sites/default/files/sheepgoat/sg_Comparison.pdf.
23. Tiezzi F., Parker-Gaddis K.L., Cole J.B., Clay J.S., Maltecca C.A. Genome-wide association study for clinical mastitis in first parity us holstein cows using single-step approach and genomic matrix re weighting procedure • PLoS One. 2015. 10: e0114919.
Review
For citations:
Selionova M.I., Aybazov A.M., Gladkikh M.Yu. The state of dairy sheep farming and prospects for the use of genomic methods to improve sheep productivity and milk composition. Sheep, goats, wool business. 2024;(1):3‑9. (In Russ.) https://doi.org/10.26897/2074-0840-2024-1-3-9