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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">wool</journal-id><journal-title-group><journal-title xml:lang="ru">Овцы, козы, шерстяное дело</journal-title><trans-title-group xml:lang="en"><trans-title>Sheep, goats, wool business</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">2074-0840</issn><publisher><publisher-name>РГАУ-МСХА</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.26897/2074-0840-2025-3-9-12</article-id><article-id custom-type="elpub" pub-id-type="custom">wool-460</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>РАЗВЕДЕНИЕ, СЕЛЕКЦИЯ, ГЕНЕТИКА</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>BREEDING, SELECTION, GENETICS</subject></subj-group></article-categories><title-group><article-title>Взаимосвязь полиморфизма ДНК-маркеров ESR и IGF-1 с мясной продуктивностью баранчиков эдильбаевской породы</article-title><trans-title-group xml:lang="en"><trans-title>Association of ESR and IGF-1 DNA marker polymorphisms with meat productivity in Edilbay ram lambs</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лушников</surname><given-names>В. П.</given-names></name><name name-style="western" xml:lang="en"><surname>Lushnikov</surname><given-names>V. P.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Владимир Петрович Лушников, доктор с.-х. наук, профессор, зав. кафедрой генетики, разведения, кормления животных и аквакультуры</p><p>410012, г. Саратов, пр-кт им. Петра Столыпина зд. 4, стр. 3.</p></bio><bio xml:lang="en"><p>Vladimir P. Lushnikov, Doctor of Agricultural Sciences, Professor, Head of the Department of Genetics, Breeding, Animal Feeding and Aquaculture</p><p>410012, Saratov, prospekt im. Peter Stolypin building 4, p. 3;</p></bio><email xlink:type="simple">lushnikovwp@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Стрильчук</surname><given-names>А. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Strilchuk</surname><given-names>A. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Андрей Александрович Стрильчук, канд. с.-х. наук, ассистент кафедры генетики, разведения, кормления животных и аквакультуры</p><p>410012, г. Саратов, пр-кт им. Петра Столыпина зд. 4, стр. 3.</p></bio><bio xml:lang="en"><p>Andrey A. Strilchuk, Candidate of Agricultural Sciences, Assistant Professor of the Department of Genetics, Breeding, Animal Feeding and Aquaculture</p><p>410012, Saratov, prospekt im. Peter Stolypin building 4, p. 3</p></bio><email xlink:type="simple">strilchuk.aa@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Гишларкаев</surname><given-names>Е. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Gishlarkaev</surname><given-names>E. I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Ерагый Исаевич Гишларкаев, директор</p><p>404064, Волгоградская область, Быковский район, с. Садовое, ул. Садовая, д. 2</p></bio><bio xml:lang="en"><p>Eragy I. Gishlarkaev, Director</p><p>404064 Bykovsky district, Volgograd region, Sadovoye village, 2 Sadovaya Street</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кудрявцева</surname><given-names>А. Д.</given-names></name><name name-style="western" xml:lang="en"><surname>Kudryavtseva</surname><given-names>A. D.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Александра Дмитриевна Кудрявцева, аспирант кафедры генетики, разведения, кормления животных и аквакультуры</p><p>410012, г. Саратов, пр-кт им. Петра Столыпина зд. 4, стр. 3.</p></bio><bio xml:lang="en"><p>Alexandra D. Kudryavtseva, Postgraduate student of the Department of Genetics, Breeding, Animal Feeding and Aquaculture</p><p>410012, Saratov. Peter Stolypin building 4, p. 3</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff-alternatives id="aff-1"><aff xml:lang="ru"><institution>ФГБОУ ВО «Саратовский государственный университет генетики, биотехнологии и инженерии имени Н.И. Вавилова»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>Saratov State University of Genetics, Biotechnology and Engineering named after N.I. Vavilov</institution><country>Russian Federation</country></aff></aff-alternatives><aff-alternatives id="aff-2"><aff xml:lang="ru"><institution>ООО «ВОЛГОГРАД-ЭДИЛЬБАЙ»</institution><country>Россия</country></aff><aff xml:lang="en"><institution>LLC “Volgograd-Edilbay”</institution><country>Russian Federation</country></aff></aff-alternatives><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>04</day><month>04</month><year>2026</year></pub-date><volume>0</volume><issue>3</issue><fpage>9</fpage><lpage>12</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лушников В.П., Стрильчук А.А., Гишларкаев Е.И., Кудрявцева А.Д., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Лушников В.П., Стрильчук А.А., Гишларкаев Е.И., Кудрявцева А.Д.</copyright-holder><copyright-holder xml:lang="en">Lushnikov V.P., Strilchuk A.A., Gishlarkaev E.I., Kudryavtseva A.D.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://wool.timacad.ru/jour/article/view/460">https://wool.timacad.ru/jour/article/view/460</self-uri><abstract><p>В работе изучена взаимосвязь полиморфизма ДНК-маркеров ESR и IGF-1 с показателями мясной продуктивности баранчиков эдильбаевской породы. Генотипирование опытного поголовья баранчиков (n=135) показало присутствие всех трёх аллельных вариантов по обоим изучаемым генам. Установлено, что баранчики с генотипом TT по гену IGF-1 достоверно превосходят сверстников с генотипом CT по живой массе, среднесуточным приростам и убойным показателям. По гену ESR выявленные различия проявлялись преимущественно от рождения до отъема по показателям живой массы и среднесуточного прироста. Полученные данные свидетельствуют о перспективности использования гена IGF-1 в качестве маркерного признака при селекции овец на повышение мясной продуктивности.</p></abstract><trans-abstract xml:lang="en"><p>The study examined the association between polymorphisms of the DNA markers ESR and IGF-1 with meat productivity traits in Edilbay ram lambs. Genotyping of the experimental group (n = 135) revealed the presence of all three allelic variants for both studied genes. It was found that ram lambs with the TT genotype of the IGF-1 gene significantly outperformed their CT peers in live weight, average daily gain, and slaughter traits. For the ESR gene, the observed differences were mainly expressed from birth to weaning in terms of live weight and average daily gain. The obtained data indicate the potential of the IGF-1 gene as a marker trait in sheep breeding aimed at improving meat productivity.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эдильбаевская порода</kwd><kwd>мясная продуктивность</kwd><kwd>ДНК-маркеры</kwd><kwd>IGF-1</kwd><kwd>ESR</kwd><kwd>генотип</kwd></kwd-group><kwd-group xml:lang="en"><kwd>Edilbay breed</kwd><kwd>meat productivity</kwd><kwd>DNA markers</kwd><kwd>IGF-1</kwd><kwd>ESR</kwd><kwd>genotype</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Горлов И.Ф., Сложенкина М.И., Колосов Ю.А., Широкова Н.В. Генетическая структура стада по генам GDF9, GH у овец Волгоградской и эдильбаевской пород ● Аграрно-пищевые инновации, 2021. № 2 (14). С. 51-59.</mixed-citation><mixed-citation xml:lang="en">Gorlov I.F., Slozhenkina M.I., Kolosov Yu.A., Shirokova N.V. Genetic structure of the flock by GDF9 and GH genes in Volgograd and Edilbaev sheep breeds. Agrarian and Food Innovations, 2021. № 2 (14). Рp. 51-59.</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Исаева Д.А., Короткевич О.С. Характеристика эдильбаевской породы овец Республики Казахстан ● Вестник НГАУ (Новосибирский государственный аграрный университет), 2021. № 4 (61). С. 157-163.</mixed-citation><mixed-citation xml:lang="en">Isaeva D.A., Korotkevich O.S. Characteristics of the Edilbaev sheep breed in the Republic of Kazakhstan ● Bulletin of NSAU (Novosibirsk State Agrarian University), 2021. № 4 (61). Рp. 157-163.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Муханов Н., Юлдашбаев Ю., Траисов Б. [et al.] Полиморфизм ДНК–маркеров мясосальных пород овец Казахстана по генам гормона роста (GH2) и инсулиноподобного фактора роста 1(IGF-1) ● Herald of Science of S. Seifullin Kazakh Agrotechnical University, 2020.</mixed-citation><mixed-citation xml:lang="en">Mukhanov N., Yuldashbayev Yu., Traisov B. [et al.] Polymorphism of DNA markers of meat–sucking sheep breeds of Kazakhstan by genes of growth hormone (GH2) and insulin-like growth factor 1 (IGF-1) ● Herald of Science of S. Seifullin Kazakh Agrotechnical University, 2020.</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Магомадов Т.А., Двалишвили В.Г., Ерохин А.И. [и др.] Мясность овец эдильбаевской породы в зависимости от уровня кормления ● Овцы, козы, шерстяное дело, 2018. № 2. С. 25-29.</mixed-citation><mixed-citation xml:lang="en">Magomadov T.A., Dvalishvili V.G., Erokhin A.I. [et al.] Meat qualities of Edilbaev sheep depending on the feeding level ● Sheep, Goats, Wool Business, 2018. № 2. Рp. 25-29.</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Юлдашбаев Ю.А., Чиндалиев А.Е., Нурбаев С.Д. [и др.] Генетическая структура популяции овец казахской тонкорунной породы по молекулярно-генетическим маркерам ДНК ● Овцы, козы, шерстяное дело, 2020. № 3. С. 2-7</mixed-citation><mixed-citation xml:lang="en">Yuldashbaev Yu.A., Chindaliev A.E., Nurbaev S.D. [et al.] The genetic structure of the population of sheep of the Kazakh fine-fleeced breed according to molecular genetic markers of DNA ● Sheep, goats, wool business, 2020. № 3. Рp. 2-7.</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Liu Q. et al. Polymorphisms of ESR1, PGR and CYP19A1 Genes and their Association with Litter Size in Small-Tailed Han Sheep ● Pakistan Journal of Zoology, 2025. V. 57. № . 2. Р. 539.</mixed-citation><mixed-citation xml:lang="en">Liu Q. et al. Polymorphisms of ESR1, PGR and CYP19A1 Genes and their Association with Litter Size in Small-Tailed Han Sheep ● Pakistan Journal of Zoology, 2025. V. 57. № . 2. Р. 539.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Moravčíková N., Trakovická A. Association of SNPs in Porcine Estrogen Receptor Gene with Carcass Traits ● SCI-ENTIFIC PAPERS ANIMAL SCIENCE AND BIOTECHNOLOGIES, 2015. V. 48. № . 1. Р. 90.</mixed-citation><mixed-citation xml:lang="en">Moravčíková N., Trakovická A. Association of SNPs in Porcine Estrogen Receptor Gene with Carcass Traits ● SCI-ENTIFIC PAPERS ANIMAL SCIENCE AND BIOTECHNOLOGIES, 2015. V. 48. № . 1. Р. 90.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Wali A.H., Abdulkareem A.A. Impact of Estrogen Receptor Gene Polymorphisms on Productive Traits and Carcass Quality in Japanese Quail ● IOP Conference Series: Earth and Environmental Science. IOP Publishing. 2025. V. 1487. № . 1. P. 012138.</mixed-citation><mixed-citation xml:lang="en">Wali A.H., Abdulkareem A.A. Impact of Estrogen Receptor Gene Polymorphisms on Productive Traits and Carcass Quality in Japanese Quail ● IOP Conference Series: Earth and Environmental Science. IOP Publishing. 2025. V. 1487. № . 1. P. 012138.</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
